Category:Cystic Fibrosis’

Living With Chronic Obstructive Pulmonary Disease

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COPD is the abbreviation for chronic obstructive pulmonary disease. It is not a particular illness, but refers more to a category of diseases. Keep in mind that the illness known as cystic fibrosis, which involves being unable to clear mucus from lungs, is often treated and discussed separately from the other COPD illnesses, though some sources have posited a link between the two. Diseases like asthma and emphysema are counted as COPD diseases.

In COPD diseases, breathing is obstructed, usually due to inflammation or clogging of the airways. Since you cannot eradicate COPD from your body, and usually cannot reverse the damage done to your respiratory system, the best thing to do is slow your sickness down. Do not try to just bear the effects as they come. Emphysema, for instance, might not be so bad at the start, but in its later stages, can cripple or even kill a person.

Then again, the COPD diseases can be quite different from each other. While emphysema is progressive, asthma tends to get less grave over time. A lot of children who frequently get attacks may find that these practically disappear once they get older. Many people who think their asthma is gone can still get an attack. True, the attacks will probably be milder and less easily triggered, but they might still do a lot of damage if they catch you off-guard. The best thing to do is to be alert, and to try to maintain good breathing practices, even if you think you are no longer in danger of an attack.

Of course, breathing exercises alone cannot be relied upon for COPD treatment, even in early stages. You might need things like asthma inhalers or oxygen tanks. In more severe cases, hospitalization and surgery might be necessary, as well. However, training your system to maximize its resources minimizes the need for these aggressive medical measures. You will save money and time if you can stay out of the hospital, and if you aren’t always worrying about getting and taking a huge array of regular medication. In addition, you will be less subject to the adverse effects of some COPD medication.

Emphysema treatment and asthma remedies would be incomplete without a thorough assessment of the way the patient breathes, and of how this breathing pattern may be improved.

If you wish, you can teach your techniques for better breathing to friends and family, even if they do not have some form of COPD. They may not be sick, but they could be healthier-if they learned better ways of using their lungs. Many people have bad breathing habits without being aware of it. One of the most common ones is to have excessively short, shallow exhalations. Remember that exhalations can be just as important as inhalations: they get rid of carbon dioxide, which can be quite toxic if it builds up in your body. Also, your body constantly produces carbon dioxide, since it is a normal waste-product of cellular respiration-the same process of which oxygen is a necessary ingredient.

COPD is by no means the end of the world. You can do something about it, especially if you are able to improve your habits on your own, instead of leaving everything up to the doctors.

Hepatitis C – New Treatment Option?

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Hepatitis C is a disease that has been associated with a number of myths and some hard facts. While Hepatitis C patients fear getting treated because they have heard all sorts of horrific stories associated with HCV treatment, the question is: ‘Can a Hepatitis C patient afford to stay away from the treatment and what will be the consequences if he or she decides to get treated?’. Also, what is the new treatment option, which was discovered in 2009, and since it is herbal, anyone can quickly apply it at home?

Hepatitis C patients who are confused if they should proceed with Hepatitis C treatment or not should consider if delaying will do them any good. The answer is an emphatic ‘No!’. By using the new herbal treatment, anyone can get rid of the infection, quickly and without any side effects, without even going to a doctor.

Delay in treatment exposes patients infected with Hepatitis C virus to two dangerous liver diseases namely, fibrosis and cirrhosis. Although, it is in common knowledge that Hepatitis C is a liver disease but almost no details of the seriousness of the disease are in knowledge of those who are infected or are susceptible to getting infected with HCV.

Fibrosis is a liver condition in which scar tissue is formed on a person’s liver. As a HCV infected patient suffers from inflammation of liver because of the virus, this can result in fibrosis if this inflammation continues for a long period. Formation of scars on our skin is a common phenomenon as often scars appear on our body as a result of injury. Although, scar tissue is protective in nature, it is not a perfect alternative to healthy skin as it has limited functions. The hepatitis c new treatment, avoids the fibrosis from forming, and cures the disease quickly.

Fibrosis is broadly split in two types, namely, pulmonary fibrosis and cystic fibrosis. While the later type is caused purely due to genetic complications, under the former type, that is, pulmonary fibrosis, patient’s lung undergoes overgrowth and hardening of scars. In many studies HCV infected patients have been diagnosed with idiopathic pulmonary fibrosis which is a variation of this disease. Generally, patients suffering from pulmonary fibrosis display symptoms such as loss of appetite, fast weight loss, chronic dry cough, fatigue and discomfort in chest. Pulmonary fibrosis patients are generally expected to survive for up to 6 years after diagnosis

Chromosome 7 and Cystic Fibrosis

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Cystic fibrosis is one of the most common genetic disorders. The genes on each chromosome control specific functions of the human body. The gene on chromosome 7 produces a protein called cystic fibrosis transmembrane regulator. Mutation in the DNA level of chromosome 7 leads to the absence of this protein which leads to cystic fibrosis.

Cystic fibrosis is a recessive disease. It means that both copies of the gene must be defective. An affected person will have abnormal cystic fibrosis transmembrane regulator gene on each chromosome 7. Therefore both biological parents must have an abnormal gene. One abnormal copy is inherited from each parent. A person with one normal gene and one abnormal gene is called a cystic fibrosis carrier. Cystic fibrosis carriers do not show any symptoms but they may pass the abnormal gene to their children. Therefore the parents can be either cystic fibrosis carriers or affected themselves.

Cystic fibrosis affects the production and function of cystic fibrosis transmembrane regulator. This disturbs the chloride transfer across cell membranes. As a result, chloride irons build up in the cells of the lungs and other organs. Water stays inside the cells to dilute the chloride and the normal secretions of the organs become thick. Mucus in the exocrine glands becomes thick and sticky. This results in blocks in the pancreas, lungs, liver and other glands. This block leads to cyst formation in glands. This results in cystic fibrosis. Cystic fibrosis causes frequent respiratory infections.

Diagnosis of cystic fibrosis is confirmed by a sweat test or DNA testing. Cystic fibrosis causes the sweat glands to secrete excessive salt. The most common symptoms of cystic fibrosis are coughing and chronic breathing difficulties. This causes repeated lung infections. The lungs and the digestive system are more affected by cystic fibrosis. The symptoms of cystic fibrosis include chronic cough, chest infection, small growth in nose, diabetes, weight loss, pancreatitis, and diarrhea. The treatment of cystic fibrosis includes oral or inhaled antibiotics, corticosteroid tablets, dietary vitamins, anti-asthma therapy and medication.

Cystic Fibrosis Research

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The primary aim of medical and scientific research on cystic fibrosis is to understand, treat and cure cystic fibrosis. The research also focuses on serious symptoms and complications of the disease.

Cystic fibrosis research on gene therapy and protein therapy has made new developments. Gene therapy using liposomes is the technique of adding a healthy copy of the gene. Protein therapy is used to repair the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Drugs for replacing the function of CFTR protein have been developed. Research groups are engaged in developing new drugs to move this protein to the membrane.

Cystic fibrosis research has spread to the area of improving symptom control which includes controlling lung infections, reducing inflammation and improving nutrition.

Another fertile area of interest is regarding the cause of cystic fibrosis. The research on genetic disorders explains the factors that regulate channel activity and their effect on the plasma membrane. This research proves that the inherited disorders of cystic fibrosis include chronic pulmonary disease and hypertension. Research done on the regulation of gene expression identifies the factors that control gene expression. The study is conducted on the effect of alterations in these factors. Researchers have developed optical imaging aids for cystic fibrosis study. Optical sensing tools are used to investigate adenosine triposphate release and its role in cystic fibrosis.

Many researches are conducted to improve the treatment of cystic fibrosis. New medicines have been invented to remove the secretions in the lungs. The removal of secretions can be measured by inhaling a small amount of radioactive gas. New methods are developed to assess the deposition and clearance of the radioactive gas. Cystic fibrosis research has proved that the effect of physiotherapy is not uniform in all patients. Physiotherapy made a positive effect in majority of patients. But some patients experience deterioration in ventilation. Researchers on this disease investigate the disordered breathing and the effect of exercise on the patients. Arm exercises result in overexpansion of lungs and this may cause breathlessness in severe cystic fibrosis patients.

Medical Problems That Arise From Having Cystic Fibrosis

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Cystic fibrosis (CF) is a common hereditary disease (genetic based disease) that affects the mucus producing tissues of the body. Many systems of the body rely on fully functioning mucus glands and when they do not work well, many medical complications can arise.

Cystic fibrosis symptoms are caused by heavy, thick, mucus. They include frequent coughing that brings up thick discolored mucus and frequent bouts of chest congestion that often leads to pneumonia. The skin may taste salty and sufferers are easily dehydrated.

The stools of a CF patient are thick, greasy, and smell foul. The patient may be eating well and have a good appetite, but fails to gain weight and thrive. Stomach pain, bloating and excessive gas is caused by too much gas in the intestines and is painful.

There are other medical problems caused by cystic fibrosis. Infertility in men is often caused by this disease. Sinusitis is caused when the space behind the eyes, nose, and forehead are being blocked by thick mucus. Nasal tissues under these condition become infected and cause sinusitis when the lining of the sinuses becomes blocked. This is very common in patients with CF. Nasal polyps may also develop in the sinuses and require surgery to remove.

Cystic fibrosis affects the lungs and bronchial tubes. The bronchial tubes are the large airways in your lungs. Bronchiectasis is a lung disease that causes these airways to become stretched and flabby. They produce pockets where mucus collects. These pockets are a breeding ground for bacteria and infection causes more damage to the bronchial tubes. This can lead to further bronchial infections and serious illness including respiratory failure.

If your lungs are not moving enough oxygen through the body, “clubbing” can be a result. Clubbing is the widening and thickening of the toes and fingers. Clubbing is a definitive sign of CF, if the condition has not already been diagnosed.

Other serious illnesses and complications include liver disease, diabetes, gallstones, collapsed lungs, and rectal prolapse. Extensive coughing and the body having problems passing stools cause rectal prolapse. This pushes the rectal tissue outside of the body.

Another serious illness that may occur because of this genetic disease is low bone density. The body does not get enough Vitamin D and this can cause rickets. Your doctor may recommend Vitamin D supplements to prevent low bone density.

Since there is currently no cure for cystic fibrosis, medical treatment is focused on treating the various symptoms and medical problems that spring up from having CF.

Cystic Fibrosis Causes Symptoms Information With Treatment

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The life expectation for people with cystic fibrosis has been steadily increasing over the past 40 years. Some people with CF have serious lung and digestive problems. Other people have more mild disease that doesn’t show up until they are adolescents or young adults. CF is caused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator (CFTR). Respiratory failure is the most dangerous consequence of cystic fibrosis. Also, the secretions block pancreatic enzymes that help digest fats and proteins, and they prevent your body from absorbing key vitamins. Treatments for cystic fibrosis are aimed at relieving symptoms and complications.

Causes of Cystic Fibrosis

The common Causes of Cystic Fibrosis:

Cystic fibrosis affects the mucus and sweat glands of the body and is caused by a defective gene.

Other bacteria may be involved.

Radiation, eg after radiotherapy to other organs in the pelvis.

The main cause of cystitis fibrosis (and other urinary tract infections) is bacteria known as coliform bacteria, which are a common occupant of the bowel.

Symptoms of Cystic Fibrosis

Some Symptoms of Cystic Fibrosis:

Weight loss, or failure to gain weight normally in childhood.

Coughing or wheezing.

Fatigue.

Infants may have salty-tasting skin.

Recurrent respiratory infections, such as pneumonia or sinusitis.

Stools that are pale or clay colored , foul smelling, or that float.

Diarrhea.

Delayed growth.

Treatment of Cystic Fibrosis

Antibiotics for respiratory infections.

Vitamin supplements, especially vitamins A, D, E, and K.

DNAse enzyme replacement therapy. The medication dornase (Pulmozyme) contains an enzyme that thins the mucus and makes it easier to cough up.

Postural drainage and chest percussion.

Lung transplant may be considered in some cases.

Pancreatic enzymes to replace those that are missing.

Research has shown that the pain reliever ibuprofen may slow lung deterioration in some children with cystic fibrosis. The results were most dramatic in children ages 5 to 13.